Integrative computational biology for cancer research

Integrative Cancer Biology & Research

Diagnosis of papillary breast lesions is challenging for most pathologists, and these lesions pose problems for patient management. I encountered an unusual breast tumor identical to solid papillary carcinoma. The histological and cytological features with immunohistochemical characteristics of this tumor are described.

Integrative Cancer Biology & Research

Purpose: Tissue transglutaminase 2 (TG2) expression is aberrantly upregulated in multiple cancer cell types, particularly those selected for resistance to chemotherapy and those isolated from metastatic sites. In this pilot study, we sought to examine the predictive and prognostic relevance of TG2 in patients treated with neoadjuvant systemic therapy (NST) for breast cancer. Methods: 47 women w...

Computational Models for Integrative and Developmental Biology

• Initial Version: march 2002. This report is also a tutorial chapter of the proceedings of the workshop " Modélisation et simulation de processus biologiques dans le contexte de la gnomique " , 17-21 mars 2002, Autran, France.

VRE for the Integrative Biology Research Consortium (IB VRE)

The IB VRE project is a JISC funded project developing a large-scale Virtual Research Environment demonstrator to investigate the use of existing collaboration frameworks to support the entire research process of a large-scale, international research consortium, namely that of the Integrative Biology (IB) project. IB is a second-round EPSRC e-Science Pilot project developing a Grid infrastructu...

Mathematics of the Integrative Cancer Biology Program